Eczema in winter can be treated with systemic medication with topical medication, the purpose of systemic medication is mainly anti-inflammatory and anti-itch, you can choose anti-histamines, sedatives and tranquilizers. The antihistamines can be chosen from ebastine tablets, loratadine tablets or olopatadine tablets, generally ebastine tablets and loratadine tablets one each night, and olopatadine tablets one each morning and evening, choose one of them, sedative and tranquilizing drugs can be chosen from diazepam and so on. Generally, glucocorticosteroid treatment is not recommended, but if the scope of the disease is relatively large and the symptoms are heavy, glucocorticosteroids, such as prednisone tablets or methylprednisolone tablets, can also be used systematically. In the acute stage, it is recommended to add intravenous treatment with calcium as well as vitamins and sodium thiosulfate, which can play a role in reducing vascular permeability and anti-allergy. If there is secondary infection, additional antibiotics, such as cephalosporins or penicillins, are needed. If the symptoms of secondary infection are more severe, drug sensitivity is needed to select specific antibiotics. For topical medications, a 3% boric acid solution is used as a wet compress when there is more exudate, and a hormonal cream, such as hydrocortisone butyrate cream, is used to reduce exudate. If the disease is secondary to infection, topical antibiotics, such as fusidic acid, etc..