Amiodarone hydrochloride can be taken for a long time, but be careful to regularly monitor the electrocardiogram electrolytes, pay attention to the adverse effects of the drug. The main effect of amiodarone is to inhibit potassium ions, able to treat tachyarrhythmia, the occurrence of atrial fibrillation patients can be long-term oral maintenance of sinus heart rate, but also can be used for the treatment of myocardial infarction after frequent premature ventricular contractions. Some patients require long-term oral medication for symptom control. Amiodarone long-term oral should pay attention to regular review of electrocardiogram, pay attention to the observation of the QT interval, regular review of electrolytes and liver function, annual review of chest X-ray to prevent the occurrence of pulmonary fibrosis. Pay attention to the adverse effects of the drug, nausea, vomiting, abdominal pain, lumbago, dyspnea and so on may occur during the administration of the drug. It is forbidden for patients who are allergic to the components of the drug, sick sinus node syndrome without pacemaker protection, lactating pregnant women, and patients with abnormal thyroid function. Long-term oral amiodarone must be applied under the guidance of a physician, choose the right dose.