The need for anesthesia for gastroscopy cannot be generalized and can be determined based on the patient’s physical condition and needs. Some patients experience significant pain or discomfort during the examination, such as nausea, vomiting, abdominal pain, and abdominal distension that are significant and cannot be tolerated. In this case, anesthesia will be given. Anesthesia is contraindicated in patients with high blood pressure, coronary artery disease and other heart diseases, and in patients who have an allergic reaction to anesthetics, significant respiratory distress, or large amounts of retained material in the stomach. In addition, special groups of people, such as the elderly or other young people with good tolerance, may choose to undergo general gastroscopy. Pain or discomfort in the throat or other GI symptoms may occur after a gastroscopy. Some of them can be relieved on their own, if not, seek medical attention.