During pregnancy, due to the normal growth and development of the embryo and the rapid changes of hormone levels in the body, the CA12-5 test value may be slightly elevated in the early stage of pregnancy, which is a normal physiological phenomenon, and does not have much clinical significance if there is no other abnormality.CA12-5 is a specific antigen marker for ovarian cancer, but it can also be elevated under the influence of diseases such as endometrial cancer, cervical cancer, breast cancer, gastrointestinal tumor, pelvic or abdominal tuberculosis, pelvic inflammation, etc. Therefore, the specificity of this test can also be elevated. Although CA12-5 is a specific antigen marker for ovarian cancer, it can also be elevated under the influence of endometrial cancer, cervical cancer, breast cancer, gastrointestinal tumors, pelvic or abdominal tuberculosis, pelvic inflammatory disease, etc. In addition, pregnant women’s own mood and poor sleep quality can also be similar to the occurrence of this situation, so the specificity of this test is not very high. If CA12-5 shows a trend of gradual increase, more than twice the normal, or even dozens of times higher, it is necessary to investigate related organic diseases.