The vaccine is not recommended for patients who are allergic to cephalosporin or penicillin and should be administered under strict medical supervision. The usual contraindications for the new crown vaccine include allergy to vaccine components, and patients who have had a severe allergic reaction to the vaccine are prohibited from receiving it. Patients who are allergic to cephalosporin and penicillin are often considered to be allergic, and there is a certain risk of vaccination with the new crown vaccine, so it is not recommended. Patients need to know the contraindications and precautions before vaccination, and if necessary, they can also consult a doctor to avoid serious adverse reactions after vaccination, which can cause serious damage to the organism. At the same time, although patients can not be vaccinated, but usually need to do a good job of daily protection, go out wearing a good mask correctly, wash your hands and disinfection diligently, special time to minimize going out to avoid infection. It is recommended that people who are allergic to cephalosporin and penicillin should be vaccinated with the new crown vaccine strictly under the guidance of a doctor and stay in the hospital for 30 minutes of observation after vaccination, and also seek help from medical personnel in time if abnormalities occur.