Compound ketoconazole ointment, if used for a long time, may produce certain hazards, which mainly lead to the formation of local skin atrophy or secondary infection. The reason for the atrophy is that compound ketoconazole ointment contains hormonal ingredients such as tretinoin, and this hormone can induce skin atrophy and even capillary dilation. So if this harm occurs, you need to stop compound ketoconazole ointment in time. Local skin can be applied topically with mucopolysaccharide polysulfate cream, which can play a role in repairing the skin epidermis to a certain extent, and has a certain repairing effect on the atrophy of the skin. At the same time, it can also improve the dilated capillaries under the skin, or you can temporarily use saline cold compresses.