Cranial repair is a common neurosurgical procedure to repair the skull in response to a traumatic brain injury resulting in a skull defect. Patients with cranial defects often have a heavy burden of thought such as insecurity, and can cause headaches, dizziness, fear of vibration and other syndromes. The longer the cranial defect, the higher the incidence of cranial defect syndrome and secondary brain damage. In order to restore the airtightness of the cranial cavity, keep the physiological intracranial pressure stable, and reduce the cranial defect syndrome. Cranial bone repair should be performed for cranial defects with a diameter of 3 centimeters or more, without muscle coverage, and without contraindications. For children with cranial defects, cranial repair can be performed after 3 years of age if the cranial defect occurs, after 3 years of age, cranial growth is relatively slow, and clinical practice has found that the surgical risk of cranial repair is positively correlated with cranial growth in different periods of growth and development, so the repair of cranial defects in children should be carried out after 3 years of age; moreover, the recovery of neurological function is fast in the first three months after the injury, and the recovery of the integrity of the cranial cavity can improve the cerebral function. Restoring the integrity of the cranial cavity as early as possible can improve the development of brain tissue and promote the recovery of neurological function. At present, we have rich experience in using PEEK material for cranial bone repair surgery, with skillful surgical techniques, and the patients can regain the appearance of the skull after the surgery, which is now a more ideal artificial repair material.