The clinical significance of a positive hepatitis B surface antibody and hepatitis B core antibody test result is that the person has been infected with the hepatitis B virus in the past, the hepatitis B virus is in the body and has made a large number of copies, and the body’s immune system has cleared the hepatitis B virus and effectively produced surface and core antibodies. The core antibody at this point is often a long-term antibody, the hepatitis B core antibody IgG, which is not protective but will remain for life. The hepatitis B surface antibody produced is a protective antibody, an antibody that the body uses to prevent the occurrence of hepatitis B virus infection; it generally does not remain for life, so it is important to review it regularly to check whether the surface antibody is present and, if it is present for a long time, to resist infection by the hepatitis B virus.