The most painful stage of a fire boil is when pus has formed locally and the patient experiences throbbing pain that is more intense. For this stage, you can go to the hospital to do incision and drainage to drain the pus, the symptoms will soon disappear, and the fire boil will soon subside. Patients need to take some anti-inflammatory drugs by mouth jointly, if cephalosporin and penicillin are not allergic, you can choose amoxicillin or cephalosporin, and locally, you can also apply compound polymyxin B ointment externally, which has the effect of anti-bacterial infection and pain relief. Patients should pay attention to, do not eat spicy, stimulating food, do not pick and scratch the skin, to avoid aggravation of infection.