Babies who do not sleep at night may firstly be caused by physiological factors such as overheating of the environment, sleep reversal, hunger, etc., which usually do not require special treatment. Secondly, it may also be caused by vitamin D deficiency, which requires medication. 1. Physiological factors: if the baby sleeps in an overheated environment may lead to nighttime sleeplessness, some babies who sleep during the day and are active at night may also be unable to sleep at night, or babies who are hungry when they sleep may also experience symptoms of nighttime sleeplessness. These are normal physiological phenomena can not need special treatment, parents to improve the above factors, the baby can sleep peacefully. 2. Vitamin D deficiency: Infants with vitamin D deficiency may wake up at night and become restless. It is recommended to use vitamin D preparations under the guidance of the doctor, for calcium deficiency patients also need to follow the doctor’s advice with calcium carbonate, calcium gluconate and other calcium treatment. Babies can not sleep at night may also be caused by other diseases such as intestinal cramps, intestinal flatulence and so on. If the baby is restless in the middle of the night, can not be soothed, it is recommended to consult a doctor, after a clear diagnosis, in accordance with the doctor’s instructions to be targeted treatment.