The clinical manifestations of grade 3 malignant breast nodules have to be analyzed on a case-by-case basis. Some patients may have no obvious clinical symptoms, while others may experience chest pain. The clinical manifestations of grade 3 malignant breast nodules vary, some patients do not have obvious clinical manifestations, and some patients have chest swelling and pain when they are emotionally excited. Some patients will have severe chest pain, accompanied by other systemic symptoms, such as the digestive system will be manifested as abdominal pain, abdominal distension, nausea, vomiting, etc.; the situation is serious or even anemia, emaciation and other cachexia. Breast nodule tertiary malignancy should be combined with the patient’s clinical manifestations, the number of nodules, size, etc., under the guidance of a professional doctor to choose the appropriate treatment plan, and actively alleviate the patient’s symptoms.