Multiple myeloma stool not pulling down is usually not serious, but if constipation causes serious intestinal infection, the situation is more serious. 1. Multiple myeloma is a kind of plasma cell malignant proliferative hematological disease, which can be clinically manifested as anemia, hypocalcemia, renal function impairment, bone damage, etc., and is mostly treated with anti-tumor chemotherapy. When it appears that the stool cannot be pulled down, it is considered to be related to constipation, and the condition is usually not serious. When constipation occurs, you can eat some fiber-rich vegetables (such as celery, spinach) and fruits, adhere to the physical exercise to promote intestinal peristalsis, and in severe cases, you can use medication such as Keserol and lactulose. 2. If constipation causes serious intestinal infection, the situation will be more serious, and it is necessary to give lactulose and other laxative treatments in time, and at the same time give levofloxacin and other anti-infective treatments. In case of multiple myeloma, the patient should be guided by the doctor, actively treat the primary disease and keep optimistic mentality. In addition, the above drugs should also be used under the guidance of doctors.