A headache followed by a toothache may be caused by pericoronitis of the wisdom teeth, acute pulpitis and other causes. 1. Wisdom tooth pericoronitis: Usually when headache and toothache occur at the same time, patients should pay attention to whether it is wisdom tooth pericoronitis. Usually the headache caused by toothache may lead to radiating pain in the head. Patients should not eat spicy and stimulating and too hard food for a few days after the onset of the disease. 2. Acute pulpitis: When the nerve of the tooth is inflamed, especially in acute pulpitis, the entire branch of the trigeminal nerve will be painful as the nerve is mainly innervated by the trigeminal nerve. This usually leads to an unclear distinction between upper and lower jaw toothache, and this pain may radiate to the temples of the face or to the ears. There are many other causes of headache followed by toothache, and patients are advised to seek active medical attention to clarify the cause and standardize treatment.