The most common treatment for severe lung infection after chemotherapy is drug treatment, and the appropriate drug anti-infection treatment is often chosen according to the symptoms, blood routine, sputum culture results, and the results of chest CT. In the process of tumor chemotherapy, because the chemotherapy drugs have a great impact on the immune function of the patient’s body, the body’s resistance and immunity is reduced compared with normal people, and it is more likely to occur lung infection. If chemotherapy patients have serious lung infections after chemotherapy, they should follow the doctor’s instructions in time to use drugs to alleviate the symptoms, avoid subsequent dyspnea and a series of respiratory failure symptoms, and if necessary, chemotherapy can be temporarily stopped. Anti-infective drugs are often based on sputum culture and drug sensitivity test to determine the drug, drug sensitivity test results come out before the use of broad-spectrum antibiotics and other drugs to temporarily control the symptoms. In addition, patients should pay attention to rest, light diet, maintain a good state of mind, adjust the treatment program under the guidance of the doctor to avoid aggravating the condition.