Fever with pus and blood at the place of surgery after ankle fracture surgery, you can take anti-inflammatory drugs, such as ampicillin, cefazolin, erythromycin, etc., to consider the presence of bacterial infection. Ankle fracture is a fracture of the ankle joint, and anti-inflammatory drugs also refer to antibiotics. Under normal circumstances, the place of surgery after ankle fracture surgery will not appear fever, pus and blood, for the existence of this situation, mostly consider the secondary bacterial infection, so at this time you can take antibiotics. Clinical doctors will choose the appropriate antibiotics according to the type of bacteria infected by the patient, such as ampicillin, amoxicillin and other penicillins, cefazolin, cefuroxime and other cephalosporins, as well as erythromycin, azithromycin and other macrolides. In addition, the affected area needs to be sterilized with iodophor under the operation of the doctor to prevent aggravating the infection. In summary, patients need to strengthen the local skin care, keep dry and clean, cooperate with the doctor to actively treat, to prevent affecting the healing of the ankle joint. The medication should be used according to the doctor’s prescription.