Bactroban is the trade name, generic name is mupirocin ointment, perianal abscess external mupirocin ointment, internal drugs are mainly antibiotics, such as penicillin, cephalosporins and so on. As a result of perianal abscess once confirmed need to carry out timely abscess incision and drainage surgery, internal medication is mainly for abscess incision and drainage surgery after infection control is not good, can be in the examination of the existence of residual abscess, the use of antibiotic treatment, such as penicillin v potassium tablets, cefixime capsules. If the patient suffers from perianal abscess accompanied by perineal necrotizing fasciitis, the use of highly effective broad-spectrum antibiotics, such as cephradine capsules and roxithromycin tablets, is required along with active incision and drainage of the abscess. Antibiotics need to be used strictly under the guidance of the doctor in full combination with the individual situation, the drugs have certain side effects to avoid adverse consequences.