If the eyes itch at night, if they are itchy at the corners of the eyes, the more you rub them, the more itchy they may become, and even in severe cases they may cause edema in the white part of the eyes, consider the case of allergy, probably due to the use of cosmetics at night, exposure to specific pollen or gas, causing conjunctival allergy. Usually these cases can be treated with Olopatadine drops or Flomipron drops for quick anti-allergy as well as anti-itch treatment. If the itching is severe, you can also take oral loratadine or cetirizine for systemic anti-allergy treatment. The effect of anti-allergy will be very fast, usually in 2-3 days can be fully recovered. If the itching is prolonged, you need to go to the hospital in time to rule out problems caused by chronic inflammation. Generally, allergies do not last long and can be controlled with the usual medication, but if they cannot be controlled, timely adjustment of medication is needed.