When these two medications are combined, it is generally recommended that spironolactone be taken orally 2-4 times a day and furosemide be taken orally once a day or every other day. Spironolactone is a synthetic steroidal compound that is a diuretic and can be used in the treatment of edematous disorders such as congestive edema, cirrhotic ascites, and renal edema, as well as an adjunctive medication in the treatment of hypertension. Spironolactone is recommended to be taken orally 2-4 times a day. Furosemide is a labeled diuretic applied in the treatment of congestive heart failure and edema, which is mainly used in edematous diseases with strong action, and the application of this class of drugs may still be effective when the application of other diuretics is ineffective. The combination of the two drugs can enhance the diuretic function and facilitate the treatment of edema. Furosemide is taken orally once a day or every other day. But be careful. Spironolactone hyperkalemia patients are prohibited, anuria, hepatic and renal insufficiency should be used with caution, renal failure and high blood potassium is contraindicated. Furosemide should be used with caution in patients with diabetes, patients with severe hepatic insufficiency should be used with caution, pregnant women should be prohibited, and children should be used with caution. Take diuretics to carry out blood potassium monitoring. The use of medication should be under the guidance of a doctor, self-medication is not recommended.