Radioactive wrinkles in the corners of the mouth are caused by diseases such as stomatitis, a clinical symptom of radioactive wrinkles that are visible in the corners of the mouth. Stomatitis, commonly known as “rotten mouth”, is characterized by flushing, blistering, cracking, erosion, crusting, and flaking of the corners of the mouth. The patient’s mouth bleeds easily and even eating and talking are affected. The triggering factor of stomatitis is the cold and dry climate, which can make the skin mucosa around the lips and corners of the mouth dry and cracked, and the surrounding germs take advantage of the infection, causing stomatitis; when the lips are dry and cracked, people often habitually lick with their tongues, which makes it easier to make the corners of the mouth dry and cracked; if the dietary intake of vitamins is reduced, resulting in a lack of B vitamins in the body, it can also lead to the occurrence of vitamin B deficiency stomatitis. So, how to check the radioactive wrinkles outward from the corners of the mouth? Here is how to check for radioactive wrinkles outward from the corners of the mouth: dry lips, maceration, moistening, erosion, cracking at the corners of the mouth, and self-conscious burning sensation. The diagnosis can be made based on clinical manifestations. Initially, the lips are dry, with erythema, edema, oozing and crusting at the corners of the mouth. When it turns chronic, the local mucosal skin is moist, cracked, rough and flaky, and occurs as radioactive wrinkles outward from the corners of the mouth. If caused by malnutrition, anemia, riboflavin deficiency can be accompanied by oral, tongue and pubic mucosal damage, such as glossy tongue, scrotal skin redness and corresponding systemic symptoms. Mostly symmetrical on both sides, but also unilateral onset. Self-perceived burning sensation. In malnourished children, pustules may appear in and around the corners of the mouth, mostly associated with septicococcal infection.