Intraoral bite rot can be localized under the guidance of a doctor to apply pain-relieving drugs, anti-inflammatory drugs, drugs to promote healing, etc., the effect is better. Intraoral bite rot, mostly manifested as traumatic ulcers, can be localized under the guidance of the doctor to use the following drugs: 1. Analgesic drugs: If the patient’s pain is obvious, the local application of lidocaine gel, compound benzocaine gel, etc., can effectively relieve pain. 2. Anti-inflammatory drugs: chlorhexidine gargle can be used to actively prevent infection. 3. Promote healing drugs: such as recombinant human epidermal growth factor gel, rehabilitation of new liquid, etc., local use can promote the healing of the bite. In addition, if the bite rot caused by bad bite and other factors, it is recommended to actively seek medical treatment for orthodontics and other treatments, the use of the above drugs need to follow the doctor’s instructions.