Back of hand spots may be caused by seborrheic keratosis, solar keratosis, removal methods include the use of depigmenting agents, freezing, superficial chemical exfoliation, laser, etc. Due to different types of diseases and individual differences, there is no best treatment. 1. Seborrheic keratosis: usually manifested as slightly higher than the skin surface, brown oval plaque, can occur in any body parts including the back of the hands, no special symptoms generally do not need treatment, if there is a rapid growth, ulceration and pain, you can choose to freeze, laser, 40% hydrogen peroxide solution or surgical treatment, etc. to remove. 2. Actinic keratosis: It is more common in laborers who are exposed to sunlight for a long time, which is manifested by the appearance of dark brown, rough and thickened plaques, accompanied by scales, and can be removed by carbon dioxide laser, ionized cautery, cryotherapy, and so on. There may be other reasons for the formation of spots on the back of the hand, it is recommended that the patient go to the hospital in time to clarify the cause of the disease, under the guidance of the doctor reasonable treatment.