What medication is used in combination with methotrexate to treat rheumatoid arthritis?

Rheumatoid arthritis can be treated with methotrexate alone or in combination with drugs such as salicylazosulfapyridine and hydroxychloroquine, depending on symptomatic relief, adverse reactions and other comprehensive judgment.
Methotrexate is the first choice for the treatment of rheumatoid arthritis, and can be used alone initially. The drug has a slow onset of action, and the common adverse effects of methotrexate are hepatic damage and bone marrow suppression, so the routine blood test, liver and kidney function should be rechecked every 4-6 weeks, and the dosage should be adjusted or replaced with other drugs according to the results. Meanwhile, the oral mucosa and digestive tract should be closely monitored during the use of the drug.
If methotrexate alone is not effective, it can be used in combination with drugs such as salicylazosulfapyridine and hydroxychloroquine to relieve joint symptoms while reducing the incidence of joint destruction or disability.
The treatment of rheumatoid arthritis is a long-term slow process, rheumatoid arthritis patients are recommended to the rheumatology and immunology department of the regular hospital for consultation, treatment as prescribed by the doctor, do not self-medication.