You can’t drink beer during the quadruple drug treatment of Helicobacter pylori. Drinking alcohol, like Helicobacter pylori infection, is a causative factor of chronic gastritis, gastric ulcers and other diseases. In addition, drinking alcohol during the medication period may also affect the activity of hepatic enzymes, and even lead to a disulfiram-like reaction, which can be life-threatening. Quadruple drug treatment of Helicobacter pylori indicates that the patient suffers from related diseases caused by Helicobacter pylori infection, such as chronic gastritis, gastric ulcers, etc. The causative factors of these diseases also include the consumption of alcohol, so drinking alcohol during the Quadruple drug treatment will not be beneficial to the recovery of chronic gastritis, gastric ulcers and other diseases, and should not be drinking alcohol. The drugs used in the quadruple pill cure for H. pylori are a proton pump inhibitor, a bismuth agent, and two antibiotics. The proton pump inhibitor and bismuth agent can be used from omeprazole and bismuth potassium citrate. The two antibiotics can be chosen from drugs such as clarithromycin, amoxicillin, metronidazole, tinidazole, quinolones, furazolidone, and tetracycline, etc. Drinking alcohol while taking the drugs will affect the activity of hepatic enzymes, and the drugs such as metronidazole and tinidazole can also cause a bisulphuric reaction, which can be life-threatening, and therefore alcohol should not be consumed. If you are taking tetracycline for H. pylori, please follow the doctor’s instructions to complete the treatment and do not drink alcohol.