Calluses, also called calluses, are found on the hands and feet, and are a protective response to long-term mechanical friction of the skin, which has a protective effect on the skin. Calluses repeatedly grow out because the area is still in the state of being rubbed or being mechanically stimulated, and as metabolism continues to increase, the dead skin will continue to superimpose with the callus block. Calluses are generally flat or slightly raised yellow or waxy yellow thickened corneous plaques, unclear borders, smooth surface, clear skin lines, due to the palms and toes are often squeezed and friction and common, diabetic patients with peripheral neuropathy, due to abnormal pressure on the bottom of the foot, also easy to form calluses. Calluses local sensory dullness, generally no discomfort, but in severe cases may appear pain, can be reduced by reducing local pressure, friction and local mechanical stimulation to relieve. If calluses recur, and there is pain, surgical removal or the use of corneal exfoliators to remove, in addition, you can also use hot water to soften and scrape with a knife to remove, this method is easy to hurt the skin, the operation should be careful to avoid causing inflammatory infections. Calluses can be reduced by reducing friction with the outside world, wearing loose and comfortable shoes, avoiding excessive physical labor, etc. to reduce the recurrence of the situation.