When large pieces of dandruff fall off from the scalp, the following conditions are considered: 1. Common psoriasis, which can be seen as well-defined plaques or erythematous plaques with silvery-white scales, is caused by genetics, immune disorders and other factors. In treatment, you can take oral compound amineptine tablets, compound glycyrrhizin capsules, local topical spray pyrithione zinc aerosol, carbotriol application, along with topical hydrocortisone butyrate ointment. If accompanied by pharyngitis, tonsillitis inflammatory infection, you also need to take oral cefaclor granules, azithromycin dry mix suspension for anti-inflammatory treatment. 2, hairy red furuncle, you can take oral Avia capsules, topical application of fluticasone propionate ointment application.