When can I breastfeed my baby after medication? The drug can be considered largely eliminated after 5 half-lives. So most of the medications can be resumed after 2-3 days of discontinuation, usually after 48 hours, and the effect of the medication on breast milk can be neglected. However, when breastfeeding is stopped, breast milk should be sucked with a breast pump to avoid back milk. The effect of daily medication on breastfeeding: 1. Antipyretic and analgesic drugs: acetaminophen (paracetamol), with less milk content, is safer for babies. Short-term applications do not need to suspend breastfeeding. 2, aminotrans: oral absorption rate is very low, it is believed that the baby does not have a significant impact, do not need to suspend breastfeeding. 3, penicillins: penicillin is a relatively safe drug for breastfeeding. The concentration of penicillins in breast milk is 2% to 20% of the blood concentration, which may occasionally cause allergy to the baby. A large number of doses may lead to diarrhea in newborns, breastfeeding is not absolutely contraindicated, but may consider suspending breastfeeding. 4, cephalosporins: with penicillin is the same as the β-lactam antibiotics, also relatively safe. But breastfeeding should avoid a lot of long-term use, otherwise it may cause the baby non-sensitive bacteria (such as Candida, etc.) infection. 5, aminoglycoside antibiotics: such as gentamicin, streptomycin, amikacin, etc.. These drugs are ototoxic and can lead to hearing impairment in newborns and should be banned. Must stop breastfeeding when you must use. 6, quinolones: norfloxacin (haloperidol), ofloxacin, levofloxacin, etc.. Clinical trials can make the development of abnormal joints in immature animals, and should not be used during lactation. Each individual is very different and has different sensitivities to different drugs, so it is recommended that breastfeeding mothers do not easily use drugs on their own when they are sick, and must communicate with your doctor about the need to stop breastfeeding and the time to stop breastfeeding when using drugs.