Clinically used glargine insulin, whether imported or domestic, is 300 units per unit. However, there is now a new drug in the clinic called glargine insulin injection U300, which is different from the previous glargine insulin and contains 450 units per unit. Since it was only approved for marketing in 2020, it has been in the clinic for a short time, so it is relatively rare, and the specific dosage and usage need to consult the prescribing doctor. The dosage of glargine insulin is a long-acting insulin and patients should choose a fixed time for subcutaneous injection every day and adjust the dosage of glargine insulin according to fasting blood sugar. Patients with diabetes need to follow the doctor’s prescription for full dosage and full course of application when using glargine insulin. Before the symptoms are fully controlled, blood sugar may be reduced, but do not easily adjust the dosage on your own to avoid serious adverse reactions.