Smooth surface of cervix may lead to cervical cancer, such as endogenous adenocellular carcinoma which is often undiagnosable by naked eye, and requires cervical cancer screening, including cervical liquid-based cytology and human papilloma virus examination. The development of cervical cancer is related to the continuous infection of human papillomavirus, even if the surface of the cervix is smooth with naked eyes, it is not certain that there is no cervical cancer, such as early stage cervical cancer, there may be no change with naked eyes; such as endogenous adenocarcinoma of the cervix, which is often undiagnosed by naked eyes, and it is necessary to carry out the combination of cervical cytology and human papillomavirus screening, and, if necessary, it is necessary to carry out colposcopy and biopsy to make a definitive diagnosis. Cervical cancer may have no obvious clinical manifestations, and its typical clinical manifestations are contact bleeding and vaginal discharge. For those who have been sexually active for more than 3 years, it is recommended that they should undergo regular screening for cervical cancer.