Corneal changes: Fuchs endothelial dystrophy has a typical shattered silvery appearance of the central posterior cornea, often called corneaguttata. The incidence increases significantly with age. Many patients with dropsy corneas have otherwise normal corneal performance and do not affect their vision. In a small number of patients, corneal stromal and epithelial edema occurs, which can cause significant vision loss. What are the prevention methods for corneal changes? 1, develop good hygiene habits, wash your hands regularly and cut your nails often. 2, do not wear contact lenses for a long time; be careful when replacing contact lenses. 3, the same as the prevention of acute conjunctivitis, mainly to cut off the source of infection with attention to eye and hand hygiene. 4.Prohibit patients from bathing and swimming in public places. 5, the treatment is mainly local medication, medication internal and acupuncture also have a certain role. 6, eat more food and fruit with cold and heat-clearing effect, such as wild rice, winter melon, bitter melon, fresh root, sugar cane, bananas, watermelon and so on. 7, early detection and treatment. Pay attention to improve the body’s immunity, especially cellular immunity, can use immunomodulatory drugs. European countries statistics show that in all corneal transplantation, about 10% of the Fuchs dystrophy, about 80% of the transplants remain clear within 2 years after surgery, but the long-term survival rate of the transplants is low. Even if the timing of surgery is appropriate, the graft will remain clear only for a limited period of time. It has been reported that in 12 patients aged 50-61 years, all graft lenses became cloudy 1-9 years after surgery, whereas in 6 patients with conical corneas operated during the same period, the graft lenses remained clear 11-15 years after surgery. In late stage patients with painful corneal blisters, when corneal transplantation or soft contact lenses are not appropriate, conjunctival flap masking, corneal interlaminar capsular mosaic and lamellar corneal interlaminar cautery are often performed to reduce symptoms.