There are many kinds of cephalosporins that pregnant women can take: Cefadroxil capsules and cefradine capsules in the first generation can be used. The first generation cephalosporins are stronger against Gram-positive cocci than Gram-negative rods, but they have a certain degree of nephrotoxicity, and pregnant women should pay attention when using them. Cefuroxime tablets, cefaclor capsules and cefprozil dispersible tablets in the second generation cephalosporins can be used. The second generation cephalosporins have a more balanced effect on Gram-positive cocci and Gram-negative bacilli, and the nephrotoxicity is also lighter than the first generation. Cefixime capsules in the third generation can be used, and its nephrotoxicity is even less, and its effect on Gram-negative bacilli is stronger than that of Gram-positive cocci, because cephalosporin is classified as a Class B drug by the U.S. Center for Food and Drug Administration and Maternal Safety Medication, and there are no side effects that cause teratogenicity and affect fetal growth and development, so pregnant women can use it throughout pregnancy. If pregnant women must use antibiotics, it is best to choose penicillin-based antibiotics, such as amoxicillin and clavulanic acid potassium.