Lymph nodes that are painful are not always cancerous. It is also possible for lymph nodes to be enlarged due to inflammatory infections, as inflammatory stimulating factors can potentially cause pain, so you cannot tell if a lymph node is cancerous based on whether or not it is painful. Most of the lymph node enlargement caused by cancer may not be accompanied by pain, of course, there are also accompanied by pain. To determine the nature of the lymph nodes, the texture of the lymph nodes is based on routine physical examination, as well as ultrasound to look at the lymph nodes and consider whether there is any fusion, or the results of puncture cytology can be used to make a preliminary diagnosis. To confirm the nature of the lymph node, it is necessary to rely on lymph node biopsy pathology, that is, complete removal of the lymph node to do laboratory tests is the most accurate. In addition, it is also necessary to consider whether the cancer is metastasized from other parts of the body, and if so, it is necessary to treat the primary cancer foci.