Nipple pain when pinched before menstruation is not necessarily a sign of pregnancy. In this case, even if you are pregnant, the hormone level of the body has not reached a certain level before menstruation, so it is difficult to show the corresponding early pregnancy reaction. This is mostly due to an imbalance in hormone levels in the body, as the growth and development of the mammary glands depends on estrogen and progesterone. If the endocrine imbalance occurs before menstruation, the secretion of estrogen is relatively high, while the secretion of progesterone is relatively low, which will cause localized swelling and pain in the breast, and the nipple localization will also appear painful when touched. It is recommended to observe the nipple carefully to exclude the pain caused by the mucous membrane tissue breakage, it is recommended to ensure good sleep and proper rest. If you have not had your period beyond the 5th day of your period, you can use an early pregnancy test to see if you are pregnant, and in most cases, the early pregnancy reaction occurs around 45 days after menopause.