Hemolysis may affect embryonic development. After the onset of hemolytic disease, the red blood cells in the fetus will be destroyed in large quantities, the number of red blood cells will be reduced, and then the fetus will suffer from anemia, and the lack of oxygen supply will also cause fetal hypoxia, which may easily lead to fetal demise if it is not treated in time. If the hemolysis is more serious, the newborn will develop bilirubin encephalopathy, when the red blood cells are destroyed, the bilirubin substance enters into the brain of the fetus, and nourishes the fetus to develop poorly. Fetuses with hemolytic disease will show typical symptoms of hemolytic disease after birth, including enlarged liver and spleen, jaundice, and so on. Symptoms of fetal enlargement can also occur during fetal life, which can easily lead to fetal arrest. Regular checkups during pregnancy are recommended. If hemolysis occurs, it is advisable to seek prompt medical attention and treatment under the guidance of a doctor.