There are two major categories of sleeping drugs that are currently in use: benzodiazepines (BDZ) and non-benzodiazepines. Benzodiazepines: Benzodiazepines are currently the most widely used hypnotic drugs, divided into short-acting, medium-acting and long-acting. 1, short-acting drugs have a half-life of 1.5 to 3 hours, including imipramine, triazolam, etc., and can be used for patients who have difficulty falling asleep. Short-acting drugs are prone to dependence, and rebound insomnia may occur after withdrawal. 2.The half-life of medium-acting drugs is 10～20 hours, including Sulezade, alprazolam, etc. It is suitable for patients with insubstantial sleep and repeated awakenings during sleep. 3, the half-life of long-acting drugs is 20 to 50 hours, including Valium, nitro Valium, clonidine, etc.. These sleeping pills are slow-acting and long-acting, and are suitable for patients with insubstantial sleep and early awakening. Patients are prone to sleepiness and fatigue the next day after taking them, so it is recommended to advance the dosing time to one hour or more before bedtime to reduce the residual effects of the drugs. Non-benzodiazepines: This is a new generation of sleeping drugs with safe and reliable efficacy, less drug dependence and rebound insomnia after withdrawal, and does not affect the sleep structure, and is now being widely used in clinical practice, with a trend to replace benzodiazepines (oxymoron to go to the early addition of Zhuo). These drugs include zolpidem, levopirone, zaleplon, etc. Barbiturates and aldehydes: including quick sleep, luminal, chloral hydrate, paraldehyde, etc.. These drugs have good hypnotic effect, but are easy to produce drug resistance, to maintain the efficacy of the need to constantly increase the dose, and long-term use can cause chronic toxicity, so the current clinical use is less.