The rheumatoid factor is considered elevated as long as it is above the upper limit of the normal range. If it is 1-3 times higher than the upper limit of the normal range, it is considered mildly elevated, and if it is more than three times the upper limit of the normal range, it is considered significantly elevated. The more common causes of significantly elevated rheumatoid factor are rheumatoid arthritis and dry syndrome, while mild elevation can be seen in patients with infections and tumors, or in some normal people. Therefore, if the rheumatoid factor is elevated, it needs to be combined with the patient’s specific clinical manifestations to make a comprehensive judgment. If there is no any physical discomfort, there is no need to deal with it and regular review is sufficient. If there is generalized symmetrical joint swelling and pain, consider rheumatoid arthritis. If there is obvious dry mouth and dry eyes, consider dry syndrome.