Nexium is known generically as esomeprazole magnesium enteric-coated tablets, and it treats reflux esophagitis. The drug is indicated for symptom control, treatment, and long-term maintenance therapy to prevent recurrence of reflux esophagitis; for eradication of Helicobacter pylori in combination with appropriate antimicrobial therapies; and for the treatment of gastric ulcers associated with treatment with nonsteroidal anti-inflammatory drugs. The drug may cause adverse reactions such as headache, diarrhea, nausea, flatulence, abdominal pain, constipation, dry mouth, and allergic reactions. The drug is contraindicated in people who are allergic to esomeprazole, other benzimidazoles. And the drug contains sucrose, it is contraindicated in patients with glucose intolerance, impaired glucose-galactose absorption or sucrase-isomaltase deficiency. When using this drug, it should be noted that this product should not be combined with nelfinavir and clopidogrel; when there are symptoms such as weight loss, vomiting blood, black stools, dysphagia, etc., you should go to the hospital in time to rule out the possibility of malignant tumors, because this product can relieve the symptoms, and delay the diagnosis; this drug will also increase the risk of bone fracture, and the patient should be based on the condition of patients to receive the lowest dose and the shortest course of treatment of the PPI. If patients need to use this drug, it is recommended that they take it under the supervision of a doctor to avoid unauthorized use.