Both Bupleurum and Semen Nodosum are heat-clearing and detoxifying herbs, which are often used together clinically, especially for post-operative treatment of cancer patients or after chemotherapy or radiotherapy, and to inhibit the regeneration of cancer cells. It is a sweet and cool herb that enters the stomach, large intestine and small intestine meridians. It can mainly clear heat and detoxify toxins, eliminate carbuncles and disperse knots, and reduce water retention and swelling, which is effective for various sore throats, damp-heat jaundice and urinary disorders. For insect and snake bites, topical treatment is also very effective. It also has the function of clearing heat, detoxifying and resolving blood stasis, stopping bleeding, inducing diuresis and reducing swelling, mainly for insect and snake bites, sore throat, nephritis, edema, as well as various bleeding disorders such as vomiting blood, epistaxis, blood in stool and blood in urine, etc. It also has good therapeutic effect for cirrhosis of the liver and ascites. The two are used together in clinical practice to complement each other and increase their detoxifying effects. However, they are both cooling herbs, so they should be used with caution in cases of physical and blood deficiency, as well as in pregnant women and patients with various deficiency conditions.