Diffuse heterogeneity of the thyroid gland generally refers to diffuse lesions of the thyroid gland with uneven echogenicity, which is considered to be caused by Hashimoto’s thyroiditis, nodular goiter and other factors, and it is recommended to consult a doctor in a timely manner. Diffuse thyroid lesions with uneven echogenicity is a kind of pathological changes under thyroid ultrasound, which is considered to be caused by Hashimoto’s thyroiditis, nodular goiter, thyroid adenoma and other disease factors; it is recommended to carry out a thyroid function test if necessary, and determine whether there is hypothyroidism or hyperthyroidism according to the results of the thyroid function test. If diffuse thyroid lesions with uneven echogenicity appear after the examination, it is recommended to go to the hospital and ask the doctor to make a judgment.