It is possible that gout is occurring in the big toe. Gout is a crystalline arthritis caused by the deposition of uric acid crystals around the joints caused by hyperuricemia, and the big toe joint is also the earliest joint involved in gout, so the big toe pain may be gout. You can further identify whether it is gout from various aspects such as triggers, attack time, symptoms and examination results. 1. triggers: there are often some obvious triggers before the attack of gout, such as eating a large amount of high purine diet, drinking alcohol, dehydration, or trauma caused by strenuous exercise, especially closed sprains, which can easily cause an attack of gout; 2. attack time: generally the acute attack of gout is at night, especially the second half of the night. 3. symptoms: the joints involved in a gout attack are usually the joints of the lower limbs, mainly the joints of the feet, with the big toe joint being the best part of the gout. The symptoms of local congestion, redness and swelling of the joints and elevated skin temperature are very obvious during an attack, and the pain is as severe as a knife cut, which can cause obvious pain when touched lightly, and the symptoms of difficulty in walking can appear the next day; 4. During the acute attack of gout, blood sampling can reveal elevated blood uric acid and the presence of urate crystals in the joint fluid, which is the gold standard for diagnosing gouty arthritis; 5. Other: after the appearance of toe pain, if it is caused by gout, it is difficult for general painkillers to relieve the pain, while it is usually effective for other diseases causing pain. When gout is suspected, medical attention should be sought as soon as possible to further confirm the diagnosis in combination with other clinical symptoms and tests. If gout is diagnosed, it should be treated aggressively with NSAIDs and glucocorticoids for analgesia and anti-infection. Pay attention to reduce the intake of high purine food, quit smoking and limit alcohol. Also pay attention to rest and drink plenty of water to prevent aggravation of the disease.