The production of epiphyllum and cannon epiphyllum are processed products of the buttercup plant epiphyllum, there is no obvious difference between the two in terms of efficacy and indications, and the difference mainly lies in the different ways of concocting. Because of the toxicity of raw epiphyllum is relatively large, usually need to be used after concocting, in order to achieve the purpose of reducing the toxicity and increasing the effectiveness. Prepared epiphyllums are mainly salted, bleached, boiled and stir-fried, while shelled epiphyllums are usually simmered and roasted in the earth. With the medicinal properties of pungency, sweetness and great heat, and attributed to the heart, kidney and spleen meridians, both of them have the effects of tonifying fire and assisting yang (replenishing the body’s yang qi), dispersing cold and removing dampness, and both of them can be used for treating gastro-abdominal pains and diarrhea due to the invasion of cold evils into the spleen and stomach, and they can be used in the treatment of impotence, uterine cold, and yin-cold oedema. Epiphyllum is toxic and may affect fetal development when taken by pregnant women, so pregnant women should be cautious in taking prepared epiphyllum and cannulated epiphyllum. Patients are advised to take Prepared Epiphyllum and Cannonical Epiphyllum under the guidance of a professional Chinese medicine practitioner’s diagnosis and avoid blind self-medication, so as to avoid ineffective treatment or serious adverse effects.