Cefixime and levofloxacin are clinically different, although they belong to the same antibiotic, but the difference also has the following aspects: 1. The two antibiotics come from different antibiotic types, cefixime belongs to the cephalosporin class of antibiotics, while levofloxacin belongs to the quinolone class of antibiotics, in clinical terms they both intersect and also have their own tendencies. 2. Cefixime has a good effect on the symptoms caused by infections of sensitive bacteria It has a good effect in relieving symptoms caused by infections of sensitive bacteria, such as tonsillitis, acute upper respiratory tract infection, acute bronchitis, pneumonia and intestinal infection or other gram-negative bacteria, gram-positive bacteria, Escherichia coli, and other related fine infections, and it also has a good therapeutic effect for urinary system infections, while levofloxacin has a better effect than cefixime for urinary system infections. 3. The difference between the two also includes that cephalexin needs to be tested for allergy because it can easily cause allergy, while levofloxacin does not need to be tested for allergy. However, the gastrointestinal reaction of levofloxacin is very obvious, often causing heartburn, acid reflux and nausea in patients, while cefixime has no such side effects.