After the gastroscopy, many patients look at the “yellow tumor” on the gastroscopy report and wonder what it is. Then let’s get to know it together. Gastric yellow tumor, also known as gastric macular tumor, lipid island, is a proliferative response of tissue cells to plasma lipid changes, is a non-neoplastic lesion, mostly occurs in middle-aged and elderly people, some cases can be accompanied by increased blood lipids, some can be complicated by systemic pathologies, such as diabetes, kidney disease or biliary cirrhosis. Are there any symptoms of gastric yellow tumor? Gastric yellow tumors often have no specific clinical symptoms or signs, but are usually detected incidentally by gastroscopy and can occur anywhere in the stomach, with the gastric sinus being the most common, followed by the antrum. Gastroscopically, it appears as a round or oval flat elevation, yellow or yellow-white, with clear borders and a slightly rough surface. Histologically, it is characterized by a collection of foam-like cells containing neutral fat in the lamina propria of the mucosa. Why is there a gastric yellow tumor? The pathogenesis of gastric yellow tumors is still unclear, but there are three views in the medical community on the mechanism of their occurrence: ① Residues of inflammatory response during gastric mucosal injury: many residual lipid-containing cell fragments are taken up by phagocytes during focal tissue destruction and repair during the inflammatory response of the organism, and eventually foam cells are formed. The foam cells are the important histopathological basis of yellow tumor, so it is believed that mucosal injury is the main causative factor. (2) Lipid metabolism disorder caused by gastric mucosal injury: localized lipid metabolism disorder in the lesion of gastric mucosal injury affects lipid transport, causing lipids to accumulate in the cells and form lipid crystals, which develop into gastric yellow tumor. (3) Intestinal epithelial metaplasia of gastric mucosa. The intestinal mucosa has the function of absorbing lipids in the gastric lumen, but the lipids cannot be transported out in time after absorption, and then gastric yellow tumor is formed. Based on the above three views, it is believed that the formation of gastric yellow tumor is based on the damage of gastric mucosa. How should it be treated? Gastric yellow tumor is more common in clinical practice, and there is no direct evidence that gastric yellow tumor can lead to gastric cancer, but it is mostly recognized as a precancerous lesion, and early removal is advocated. Most of them can be removed at once by biopsy forceps, while those with larger diameter can be removed in parts or by microwave or argon ion coagulation. If gastric xanthoma is accompanied by superficial gastritis, atrophic gastritis and other diseases, the accompanying diseases should be actively treated to promote the recovery of gastric mucosal function. Doctor, what should I pay attention to? Gastric mucosal damage is closely related to diet. It is important to change bad habits in life, quit smoking and alcohol, and avoid spicy and stimulating foods. In addition, good eating habits are important for everyone.