Treatment of spastic paraplegia includes medication, physical therapy, surgery and so on. 1. Drug treatment: the application of drugs such as chlorophenylbutyric acid, ethylprednisolone hydrochloride, levodopa, phenazopyridine, etc. is favorable to reduce the symptoms of myasthenia gravis. 2. Physical therapy: including acupuncture, electrical stimulation, massage can reduce the symptoms of some patients. 3. Surgery: Selective spinal nerve posterior rhizotomy (SPR), peripheral neurotomy, orthopedic surgery and other surgical methods have some effect in the treatment of spastic paraplegia, but surgical methods are invasive treatments, which have certain risks, and should be chosen carefully and the indications for surgery should be strictly controlled. Besides, rehabilitation training is also beneficial for some spastic paraplegia. When spastic paraplegia occurs, one should go to a regular hospital and follow the doctor’s instructions for treatment.