Lumbar spine tuberculosis causing sciatic nerve pain can take rest and other general treatment, anti-tuberculosis or pain medication, local physical therapy, and surgery if necessary. 1. General treatment: when in pain, patients are advised to rest, avoid exertion, and wear a waist cuff when necessary. 2. Drug treatment: anti-tuberculosis drugs such as isoniazid, ethambutol and rifampicin, and anti-inflammatory and pain relieving drugs such as celecoxib can be used in case of pain. 3. Surgical treatment: If abscess formation is caused by lumbar tuberculosis, it can be treated by puncture and drainage of abscess or streptomycin irrigation. For lumbar spine tuberculosis persistent, can remove the diseased vertebrae, rebuild local stability. Lumbar spine tuberculosis caused sciatic nerve pain is recommended to go to the hospital in time, early formal treatment, in order to reduce the adverse effects of the disease.