Clopidogrel is not effective when taken 25mg a day, and the generally recommended dose is 75mg/day. Clopidogrel belongs to a kind of antiplatelet aggregation drug, can selectively inhibit the binding of adenosine diphosphate ADP and its receptor on the platelet, so as to effectively inhibit platelet aggregation, oral absorption is rapid, the plasma protein binding rate of about 98%. The recommended dose of clopidogrel for the prevention and treatment of myocardial infarction, ischemic encephalopathy, cerebral infarction, occlusive vasculitis, and atherosclerosis is 75 mg per day.Additionally in patients with acute coronary syndromes, a single loading dose of clopidogrel should be initiated at 300 mg, followed by 75 mg/day of continuous dosing. In particular, patients with recent stroke, myocardial infarction, or peripheral arterial embolic disease are required to take a clopidogrel dose of 75mg or more in order to minimize the occurrence of acute cardiovascular and cerebrovascular events. The adverse drug reactions of clopidogrel are similar to those of aspirin, with common adverse reactions including gastrointestinal discomfort, skin rash, and rare adverse reactions such as internal bleeding and severe granulocytopenia. It is recommended that clopidogrel be taken under the supervision of a doctor. It is contraindicated for those who are allergic to the components of the drug, diseases with bleeding tendency, peptic ulcers, as well as patients with hepatic and renal insufficiency, and should be used with caution by pregnant and lactating women. You can take the drug with meals to reduce the irritating effect of the drug on the gastrointestinal mucosa. It is recommended to take under the guidance of a doctor, not blindly use the drug on their own.