Whether advanced follicular lymphoma is life-threatening or not needs to be judged according to the condition. 1. If the treatment effect is good, the survival time is long; however, if the condition suddenly shows deterioration, it will affect the life. 2. A small portion of advanced follicular lymphoma starts without symptoms. Although the tumor invades many lymph nodes or bone marrow all over the body, there are no symptoms, so there is no need to go for active intervention at this time. Even if advanced follicular lymphoma is incurable, early intervention does not prolong survival. 3. However, once symptoms appear, such as lymph nodes pressing on organs, causing anemia, thrombocytopenia, obvious wasting, fever, etc., at this time, chemotherapy should be actively carried out, which can control the progression of the disease. If the diagnosis of follicular lymphoma advanced stage, it is recommended to timely hospital consultation, standardized treatment under the guidance of doctors.