Generally acute leukemia can be survived for about 3 months without drug intervention; chronic leukemia can be survived for about 5 years without intervention. Survival time is generally often related to the type of disease and whether it is treated aggressively. Acute leukemia and chronic leukemia can significantly prolong survival if they are treated with standardized treatments such as chemotherapy and hematopoietic stem cell transplantation. 1. Without drug intervention: acute leukemia is relatively dangerous, without timely intervention, the survival period is very short, the average survival period is only about 3 months, and the shorter ones even die a few days after diagnosis; chronic leukemia, especially chronic lymphocytic leukemia, can survive for about 5 years without intervention. 2. After active treatment (1) The treatment modalities for acute myeloid and acute lymphoblastic leukemia mainly include chemotherapy and hematopoietic stem cell transplantation, which can improve survival to a certain extent. Drugs include cytarabine, Zoerythromycin, cyclophosphamide and so on. (2) Chronic granulocytic leukemia, treated with tyrosine kinase inhibitors and other molecularly targeted drugs such as imatinib, the survival of patients is significantly prolonged, with a 10-year survival rate of more than 85%. (3) Acute myeloid leukemia type M3, which has also become acute promyelocytic leukemia, is treated with all-trans retinoic acid, arsenic trioxide, and other drugs, and the vast majority of patients can achieve clinical cure and long-term survival. Patients with leukemia can improve their quality of life and prolong their survival to a certain extent after active and standardized treatment under the guidance of physicians.