12 years old girl face long spots may be freckles, white chaff rash, macular chaff rash, etc., can follow the doctor’s instructions with medication or other measures for treatment. 1. Freckles: If it is clear that it is freckles, patients can follow the doctor’s instruction to use 30%~35% trichloroacetic acid solution or phenol spot-coating, which can make the freckles peeling off, but the current clinical application is less. Clinical freckles are often treated with Q-switched ruby laser with wavelength of 694nm, emerald green gem laser with wavelength of 755nm or intense pulsed light. Sunlight should be avoided, and shading agent can be used when going out. 2. White chaff rash: some white chaff rash can subside by itself, but daily should avoid excessive cleaning or reasonable application of moisturizing cream to improve the dry state of the skin. Some patients can use silicone oil cream, urea ointment and other topical moisturizer, if the skin appears inflammation, redness, etc., can use tacrolimus ointment, glycerine lotion and other medications. 3. Streptococcal furuncle: ketoconazole cream, miconazole cream and other antifungal topical preparations for treatment, but also 2% ketoconazole lotion, 2.5% selenium disulfide and other drugs to improve the skin condition. For those who are not effective with simple topical drugs and have large skin lesions, oral antifungal drugs, such as clotrimazole and ketoconazole, can be taken. Facial pigmentation may also be related to other diseases, it is recommended that parents take the 12-year-old girl with long facial spots to a regular hospital for medical examination, clear cause of the disease to follow the doctor’s instructions for treatment, not to use drugs or prescriptions. Daily attention to strengthen the skin care, avoid foreign body friction stimulation.