A uric acid value of 680 μmol/L alone cannot determine whether or not uremia is present, because uremia is an advanced manifestation of renal insufficiency in patients. At this time, kidney function is severely impaired, and although elevated uric acid can be seen, relying on elevated uric acid alone does not confirm the diagnosis of uremia. The diagnosis of uremia is mainly based on the glomerular filtration rate, which is measured by creatinine level. When the glomerular filtration rate is <15ml/min 1.73m2, it indicates that the uremic phase has been reached. Clinically elevated uric acid can also be caused by other diseases, such as hyperuricemia. Therefore, when uric acid is detected at 680 μmol/L, the patient can be further examined for clarification. The diagnosis of hyperuricemia can be confirmed only if the uric acid is elevated in more than 2 consecutive tests. If the diagnosis of hyperuricemia is confirmed, treatment is also required in different cases. When uric acid is below 540 μmol/L, uric acid-lowering therapy is not usually recommended. Uric acid levels can usually be regulated through lifestyle and dietary changes. When uric acid exceeds the above threshold, the role of lifestyle regulation is no longer obvious, and medication is needed to lower uric acid. Commonly used drugs include allopurinol tablets, febuxostat tablets and benzbromarone tablets, which can keep the blood uric acid at a low level, reduce the damage of kidney function and slow down the progress of kidney failure. If uric acid is not controlled in time, it will easily lead to further decline of chronic kidney function and even develop into uremia, at which time kidney transplantation is needed.