Sudden eye pain can not open may be related to eye trauma, acute closed angle glaucoma acute attack, intracranial aneurysm and so on. 1. Eye trauma: when a foreign body enters the eye or the eyeball is scratched, it will cause obvious foreign body sensation and tingling sensation, resulting in the inability to open the eye. 2. Acute closed angle glaucoma acute attack: acute attack due to increased intraocular pressure, there may be severe eye swelling, tearing, inability to open the eyes and other symptoms, accompanied by nausea, vomiting and other systemic symptoms. 3. Intracranial aneurysm: it may be caused by arteriosclerosis, infection, trauma, etc. When the aneurysm presses on the motoneuron nerve, it leads to motoneuron nerve paralysis and sudden inability to open the eyes. Sudden eye pain can not open, it is recommended to consult a doctor in a timely manner, follow the doctor’s instructions and then further relevant examinations, with the help of the doctor to clarify the cause, and targeted treatment or treatment.